2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMSB15A Gene (Entity type)	-0.005364943
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CIRBP Gene (Entity type)	-0.0048785787
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TES Gene (Entity type)	-0.005393632
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.5041531324386597
SID11111646 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.6691998839378357
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	-0.0076169856
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.3314546048641205
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT18 Gene (Entity type)	-0.005160226
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL4A5 Gene (Entity type)	-0.0052875034
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARL4C Gene (Entity type)	0.009774279

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMSB15A
Gene (Entity type)
-0.005364943

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CIRBP
Gene (Entity type)
-0.0048785787

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TES
Gene (Entity type)
-0.005393632

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.5041531324386597

SID11111646
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.6691998839378357

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
-0.0076169856

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.3314546048641205

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT18
Gene (Entity type)
-0.005160226

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL4A5
Gene (Entity type)
-0.0052875034

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARL4C
Gene (Entity type)
0.009774279

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