2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMSB15A Gene (Entity type)	-0.005364943
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CIRBP Gene (Entity type)	-0.0048785787
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TES Gene (Entity type)	-0.005393632
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.5041531324386597
SID11111646 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.6691998839378357
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	-0.0076169856
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.3314546048641205
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT18 Gene (Entity type)	-0.005160226
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL4A5 Gene (Entity type)	-0.0052875034
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARL4C Gene (Entity type)	0.009774279

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMSB15A
Gene (Entity type)
-0.005364943

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CIRBP
Gene (Entity type)
-0.0048785787

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TES
Gene (Entity type)
-0.005393632

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.5041531324386597

SID11111646
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.6691998839378357

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
-0.0076169856

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.3314546048641205

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT18
Gene (Entity type)
-0.005160226

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL4A5
Gene (Entity type)
-0.0052875034

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARL4C
Gene (Entity type)
0.009774279

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.