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SC5D (Gene)

Ensembl Gene ID: ENSG00000109929

Entrez Gene ID: 6309

Description: sterol-C5-desaturase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SC5D's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SC5D.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SC5D.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SC5D.

Gene Sets (3581)

LINCS L1000 Chem Pert Consensus Sigs (1098)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (743)

A gene set library provided by LINCS

rummageo gene perturbations (187)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1276)

A gene set library provided by LINCS

rummageo chemical perturbations (268)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (6)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SID11113547 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.009521739
	XMD-1499 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.005197067
	iloperidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.011247429
	4-hydroxytamoxifen Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.005617528
	peucedanin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	-0.012557244
	(3R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-chlorobenzo[b]thiophene-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.0037540053
	[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.018341426
	N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.004579495
	KB-R7943 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.008944948
	N'-((5-methylfuran-2-yl)methylene)-2-phenoxybenzohydrazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	-0.008985988

SID11113547
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.009521739

XMD-1499
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.005197067

iloperidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.011247429

4-hydroxytamoxifen
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.005617528

peucedanin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
-0.012557244

(3R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-chlorobenzo[b]thiophene-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.0037540053

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.018341426

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.004579495

KB-R7943
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.008944948

N'-((5-methylfuran-2-yl)methylene)-2-phenoxybenzohydrazide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
-0.008985988

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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