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TWS119 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TWS119's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	-0.00534448
	TWS119 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.0038263835
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AREG Gene (Entity type)	-0.0048928605
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	-0.0048054215
	TWS119 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	IBRUTINIB::US9108973, Ref 1::US9181263, 1::US9278100, 1 Compound (Entity type)	0.3736509680747986
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NEDD9 Gene (Entity type)	-0.0051262756
	TWS119 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.003952202
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP4 Gene (Entity type)	-0.00486452
	TWS119 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	-0.0051334566
	TWS119 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Glycogen synthase kinase-3 beta Protein (Entity type)	IC50

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
-0.00534448

TWS119
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
0.0038263835

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AREG
Gene (Entity type)
-0.0048928605

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
-0.0048054215

TWS119
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
IBRUTINIB::US9108973, Ref 1::US9181263, 1::US9278100, 1
Compound (Entity type)
0.3736509680747986

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NEDD9
Gene (Entity type)
-0.0051262756

TWS119
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.003952202

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP4
Gene (Entity type)
-0.00486452

TWS119
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN1
Gene (Entity type)
-0.0051334566

TWS119
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Glycogen synthase kinase-3 beta
Protein (Entity type)
IC50

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