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SKI-606 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SKI-606's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D3 Gene (Entity type)	0.010516338
	SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase SIK1 Protein (Entity type)	IC50
	SKI-606 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPON1 Gene (Entity type)	-0.0037535713
	SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fyn Protein (Entity type)	IC50
	SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF4EBP1 Gene (Entity type)	0.006239674
	SKI-606 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	-0.004512968
	SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-G-associated kinase Protein (Entity type)	Kd
	SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Lck Protein (Entity type)	Kd
	SKI-606 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PD-407824 Compound (Entity type)	0.5230044722557068
	SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACAT2 Gene (Entity type)	0.007238367

SKI-606
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSC22D3
Gene (Entity type)
0.010516338

SKI-606
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase SIK1
Protein (Entity type)
IC50

SKI-606
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPON1
Gene (Entity type)
-0.0037535713

SKI-606
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Fyn
Protein (Entity type)
IC50

SKI-606
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF4EBP1
Gene (Entity type)
0.006239674

SKI-606
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SELENOP
Gene (Entity type)
-0.004512968

SKI-606
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cyclin-G-associated kinase
Protein (Entity type)
Kd

SKI-606
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Lck
Protein (Entity type)
Kd

SKI-606
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PD-407824
Compound (Entity type)
0.5230044722557068

SKI-606
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACAT2
Gene (Entity type)
0.007238367

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