N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPNMB Gene (Entity type)	0.009980446
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GEM Gene (Entity type)	-0.010320905
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NUPR1 Gene (Entity type)	0.008649619
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	G0S2 Gene (Entity type)	-0.010911012
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL6 Gene (Entity type)	-0.00874303
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ENPP2 Gene (Entity type)	0.008808742
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.009012771
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CAV2 Gene (Entity type)	0.008961621
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FGFR3 Gene (Entity type)	0.009723461
N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	0.009173241

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPNMB
Gene (Entity type)
0.009980446

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GEM
Gene (Entity type)
-0.010320905

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NUPR1
Gene (Entity type)
0.008649619

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
G0S2
Gene (Entity type)
-0.010911012

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL6
Gene (Entity type)
-0.00874303

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ENPP2
Gene (Entity type)
0.008808742

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINA1
Gene (Entity type)
0.009012771

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CAV2
Gene (Entity type)
0.008961621

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FGFR3
Gene (Entity type)
0.009723461

N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(2-((2-(methylsulfonyl)ethylamino)methyl)thiazol-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
0.009173241

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