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Rociletinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Rociletinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Rociletinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	0.0038665102
	Rociletinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAGEA3 Gene (Entity type)	-0.0044961483
	Rociletinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D3 Gene (Entity type)	0.0038255744
	Rociletinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PDGFC Gene (Entity type)	-0.0051105116
	Rociletinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.0062851356
	Rociletinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SGI-1776 Compound (Entity type)	0.3153408467769623
	9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rociletinib Compound (Entity type)	0.3187147676944732
	Rociletinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLS3 Gene (Entity type)	0.0050861523
	Rociletinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	0.35456383228302
	Rociletinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CKB Gene (Entity type)	-0.004979174

Rociletinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCN1
Gene (Entity type)
0.0038665102

Rociletinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAGEA3
Gene (Entity type)
-0.0044961483

Rociletinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSC22D3
Gene (Entity type)
0.0038255744

Rociletinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PDGFC
Gene (Entity type)
-0.0051105116

Rociletinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.0062851356

Rociletinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SGI-1776
Compound (Entity type)
0.3153408467769623

9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Rociletinib
Compound (Entity type)
0.3187147676944732

Rociletinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLS3
Gene (Entity type)
0.0050861523

Rociletinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
0.35456383228302

Rociletinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CKB
Gene (Entity type)
-0.004979174

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