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SGI-1776 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SGI-1776's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SGI-1776 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ACTC1 Gene (Entity type)	-0.0029046892
	SGI-1776 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase haspin Protein (Entity type)	IC50
	SGI-1776 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.00436303
	SGI-1776 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1M Gene (Entity type)	-0.0028511805
	SGI-1776 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.005836143
	netupitant Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SGI-1776 Compound (Entity type)	0.3179313540458679
	SGI-1776 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TM7SF2 Gene (Entity type)	0.0028033236
	SGI-1776 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FDFT1 Gene (Entity type)	0.003523437
	SGI-1776 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Tetrandrine Compound (Entity type)	0.4988230168819427
	SGI-1776 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase pim-1 Protein (Entity type)	IC50

SGI-1776
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ACTC1
Gene (Entity type)
-0.0029046892

SGI-1776
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase haspin
Protein (Entity type)
IC50

SGI-1776
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.00436303

SGI-1776
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1M
Gene (Entity type)
-0.0028511805

SGI-1776
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.005836143

netupitant
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SGI-1776
Compound (Entity type)
0.3179313540458679

SGI-1776
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TM7SF2
Gene (Entity type)
0.0028033236

SGI-1776
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FDFT1
Gene (Entity type)
0.003523437

SGI-1776
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Tetrandrine
Compound (Entity type)
0.4988230168819427

SGI-1776
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase pim-1
Protein (Entity type)
IC50

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