8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein HSP 90-beta Protein (Entity type)	EC50
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM97 Gene (Entity type)	0.014618449
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPH1 Gene (Entity type)	0.027655793
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	-0.018751536
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.027297886
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.013412353
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP4 Gene (Entity type)	-0.0138921505
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPB1 Gene (Entity type)	0.012166333
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	-0.024084998
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.017149124

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein HSP 90-beta
Protein (Entity type)
EC50

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM97
Gene (Entity type)
0.014618449

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPH1
Gene (Entity type)
0.027655793

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
-0.018751536

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA1
Gene (Entity type)
-0.027297886

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LIF
Gene (Entity type)
-0.013412353

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP4
Gene (Entity type)
-0.0138921505

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPB1
Gene (Entity type)
0.012166333

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
-0.024084998

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA2
Gene (Entity type)
-0.017149124

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