TIPARP (Gene)

Entrez Gene ID: 25976

Description: TCDD inducible poly(ADP-ribose) polymerase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TIPARP's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TIPARP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TIPARP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TIPARP.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TIPARP.

Gene Sets (3099)

LINCS L1000 Chem Pert Consensus Sigs (821)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (9)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (760)

A gene set library provided by LINCS

rummageo gene perturbations (210)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (469)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (516)

A gene set library provided by LINCS

rummageo chemical perturbations (311)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
LFM-A13 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.0070657986
D4476 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	-0.005699624
KIN001-043 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.010174313
Digoxigenin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.012246914
terreic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	-0.015005919
SA-1456039 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.009288317
SID11113966 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.0144037
4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl)-N-quinolin-8-yl-benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	-0.009621474
orantinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.0053370018
JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.008307026

LFM-A13
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.0070657986

D4476
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
-0.005699624

KIN001-043
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.010174313

Digoxigenin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.012246914

terreic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
-0.015005919

SA-1456039
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.009288317

SID11113966
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.0144037

4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-N-quinolin-8-yl-benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
-0.009621474

orantinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.0053370018

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.008307026

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Knowledge Graph Assertions

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CFDE Workbench

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Community

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.