MYLK (Gene)

Description: myosin light chain kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MYLK's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MYLK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MYLK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MYLK.

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Gene Sets (1130)

LINCS L1000 Chem Pert Consensus Sigs (905)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (169)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (9)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (30)

A gene set library provided by GTEx

IDG Drug Targets 2022 (10)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.003575804
ursodiol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	0.0051112543
Rilpivirine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.0037469505
5-(4,4-dimethyl-2-thioxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.004622017
tiagabine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.0030620496
salvinorin A Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.004679415
Trimethobenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.004145423
NSI-189 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.004304171
enprofylline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.008985929
ACDPP Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.013983939