1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)'s neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A11 Gene (Entity type)	-0.003162669
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	-0.0032628006
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	-0.0028250846
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.003575804
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Angiotensin-converting enzyme Protein (Entity type)	IC50
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	-0.0026404324
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.0035574075
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEMIP Gene (Entity type)	-0.0035805653
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GUCY1A1 Gene (Entity type)	0.0024713625
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AREG Gene (Entity type)	-0.0028355157