1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)'s neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A11 Gene (Entity type)	-0.003162669
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	-0.0032628006
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	-0.0028250846
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	-0.003575804
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Angiotensin-converting enzyme Protein (Entity type)	IC50
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	-0.0026404324
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.0035574075
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEMIP Gene (Entity type)	-0.0035805653
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GUCY1A1 Gene (Entity type)	0.0024713625
1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AREG Gene (Entity type)	-0.0028355157

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC7A11
Gene (Entity type)
-0.003162669

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SELENOP
Gene (Entity type)
-0.0032628006

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
-0.0028250846

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MYLK
Gene (Entity type)
-0.003575804

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Angiotensin-converting enzyme
Protein (Entity type)
IC50

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A9
Gene (Entity type)
-0.0026404324

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.0035574075

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CEMIP
Gene (Entity type)
-0.0035805653

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GUCY1A1
Gene (Entity type)
0.0024713625

1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid (Ramipril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AREG
Gene (Entity type)
-0.0028355157

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.