FXR1 (Gene)

Description: FMR1 autosomal homolog 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FXR1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FXR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FXR1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FXR1.

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Gene Sets (695)

LINCS L1000 Chem Pert Consensus Sigs (354)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (329)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (7)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.013091374
Geldanamycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.010370491
4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-benzene-1,3-diol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.009942637
Physostigmine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	-0.002602104
1-[3-(4,4-diphenylhexahydro-1-pyridinyl)propyl] 3-methyl 4,6-dimethyl-2-phenyl(3-nitro)-3,6-cyclohexadiene-1,3-dicarboxylate (niguldipine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	-0.0031600583
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.010726058
Ganetespib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.017783253
PP-242 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.026671737
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.017050762
17-allyl-17-demethoxygeldanamycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.012428736