(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	-0.012418304
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EMP1 Gene (Entity type)	-0.011188544
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AGR2 Gene (Entity type)	0.0096216565
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMDHD2 Gene (Entity type)	-0.01170669
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CENPU Gene (Entity type)	-0.009995655
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	0.010020445
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TUBB2A Gene (Entity type)	-0.013340146
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLEC2B Gene (Entity type)	-0.0103099225
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJB6 Gene (Entity type)	0.009329402
(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYZ Gene (Entity type)	0.009097739

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
-0.012418304

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EMP1
Gene (Entity type)
-0.011188544

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AGR2
Gene (Entity type)
0.0096216565

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMDHD2
Gene (Entity type)
-0.01170669

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CENPU
Gene (Entity type)
-0.009995655

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
0.010020445

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TUBB2A
Gene (Entity type)
-0.013340146

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLEC2B
Gene (Entity type)
-0.0103099225

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJB6
Gene (Entity type)
0.009329402

(2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRYZ
Gene (Entity type)
0.009097739

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.