CES1 (Gene)

Description: carboxylesterase 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CES1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CES1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CES1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CES1.

Submit

Gene Sets (1991)

LINCS L1000 Chem Pert Consensus Sigs (1098)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (879)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Flunixin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.007427352
BAY 367620 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.007870125
Tranylcypromine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.0041050008
CHIR-265/RAF-265 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.005290301
Bimatoprost Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.0031177853
6-(2-Isopropyl-benzenesulfonyl)-5-nitro-quinolin-8-ylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	0.009519293
Copanlisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.0069284006
CES1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Isonicotinic Acid Metabolite (Entity type)
Roflumilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	-0.0037656417
Thiomersal Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	0.0058701434