PCSK1N (Gene)

Description: proprotein convertase subtilisin/kexin type 1 inhibitor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PCSK1N's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PCSK1N.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PCSK1N.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PCSK1N.

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Gene Sets (1198)

LINCS L1000 Chem Pert Consensus Sigs (479)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (27)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (670)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (7)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
AT1-SHH-09 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	-0.0032973336
PSH-003 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.009945091
SA-1920327 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.016270293
Formononetin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.014846022
ST-4070043 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.009546383
odanacatib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.0037999738
SA-1922927 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	0.0106567
Pergolide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	-0.007347831
dipropyl-5-CT Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK1N Gene (Entity type)	-0.006727005