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Pergolide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Pergolide's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Pergolide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2C Protein (Entity type)
	Pergolide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.009301118
	Pergolide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TTC39A Gene (Entity type)	-0.006504735
	Pergolide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	D Protein (Entity type)	Ki
	Pergolide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMYD2 Gene (Entity type)	0.006585984
	Pergolide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2D6 Protein (Entity type)	IC50
	Pergolide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-2A adrenergic receptor Protein (Entity type)
	Pergolide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Proparacaine Compound (Entity type)	0.2668156325817108
	Pergolide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CX3CR1 Gene (Entity type)	-0.007248038
	Pergolide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 1A Protein (Entity type)

Pergolide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 2C
Protein (Entity type)

Pergolide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.009301118

Pergolide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TTC39A
Gene (Entity type)
-0.006504735

Pergolide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
D
Protein (Entity type)
Ki

Pergolide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMYD2
Gene (Entity type)
0.006585984

Pergolide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2D6
Protein (Entity type)
IC50

Pergolide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-2A adrenergic receptor
Protein (Entity type)

Pergolide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Proparacaine
Compound (Entity type)
0.2668156325817108

Pergolide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CX3CR1
Gene (Entity type)
-0.007248038

Pergolide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 1A
Protein (Entity type)

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