TMEM176A (Gene)

Description: transmembrane protein 176A

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TMEM176A's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TMEM176A.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TMEM176A.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TMEM176A.

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Gene Sets (1478)

LINCS L1000 Chem Pert Consensus Sigs (804)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (666)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Iguratimod Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.0055330005
SID11111654 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	-0.00543563
(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.010191515
SA-1460136 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.012843952
Zidovudine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.004771528
4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	-0.0042338595
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	-0.004404886
SA-89735 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.013634124
N4-(3-Bromo-phenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.010737173
palomid-529 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	0.003126429