TMPRSS4 (Gene)

Description: transmembrane serine protease 4

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TMPRSS4's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TMPRSS4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TMPRSS4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TMPRSS4.

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Gene Sets (619)

LINCS L1000 Chem Pert Consensus Sigs (287)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (12)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (296)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (9)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
macula densa epithelial cell Anatomy (Entity type)	Has marker gene in kidney Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)	0.007820809
[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)	0.0036250113
hydrastine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)	-0.008778922
KFGENEBIN:TMPRSS4-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)
Terconazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMPRSS4 Gene (Entity type)	-0.0064284983