HSD11B1 (Gene)

Description: hydroxysteroid 11-beta dehydrogenase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HSD11B1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HSD11B1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HSD11B1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HSD11B1.

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Gene Sets (1321)

LINCS L1000 Chem Pert Consensus Sigs (641)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (666)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

IDG Drug Targets 2022 (3)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
HSD11B1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	corticosterone Metabolite (Entity type)
N-formylmethionylalanine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	-0.016274137
CGP53353 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	-0.009253498
HSD11B1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	11-dehydrocorticosterone Metabolite (Entity type)
SA-242443 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	0.011374369
HSD11B1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	NADP Metabolite (Entity type)
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	0.004784034
acefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	0.020023642
Hemicholinium-3 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	0.012071829
MW-SHH-250 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	-0.0036126806