(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PFKL Gene (Entity type)	-0.0049893833
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IKBKE Gene (Entity type)	-0.0044063595
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC26A2 Gene (Entity type)	-0.0046195965
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.0051779496
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peroxisome proliferator-activated receptor alpha Protein (Entity type)	EC50
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B1 Gene (Entity type)	0.004784034
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1 Gene (Entity type)	0.004346749
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LMO2 Gene (Entity type)	0.0058168983
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPON2 Gene (Entity type)	0.0044434564
(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peroxisome proliferator-activated receptor gamma Protein (Entity type)	EC50

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PFKL
Gene (Entity type)
-0.0049893833

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IKBKE
Gene (Entity type)
-0.0044063595

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC26A2
Gene (Entity type)
-0.0046195965

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
0.0051779496

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peroxisome proliferator-activated receptor alpha
Protein (Entity type)
EC50

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSD11B1
Gene (Entity type)
0.004784034

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGF1
Gene (Entity type)
0.004346749

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LMO2
Gene (Entity type)
0.0058168983

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPON2
Gene (Entity type)
0.0044434564

(S)-3-(4-(4-(methylsulfonyloxy)phenethoxy)phenyl)-2-ethoxypropanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peroxisome proliferator-activated receptor gamma
Protein (Entity type)
EC50

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Knowledge Graph Assertions

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