DDB2 (Gene)

Description: damage specific DNA binding protein 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DDB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DDB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DDB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DDB2.

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Gene Sets (470)

LINCS L1000 Chem Pert Consensus Sigs (343)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (127)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
amsacrine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.014252856
[1,4']Bipiperidinyl-1'-carboxylic acid (S)-4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-yl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.012607049
topotecan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.02362716
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	-0.009209266
Fluorouracil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.0040971707
Camptothecin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.015107357
doxorubicin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.010571315
Etoposide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.008098082
Selinexor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.013154801
Ingenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	-0.01017062