2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	-0.009209266
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCP2 Gene (Entity type)	0.011872408
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSMG1 Gene (Entity type)	-0.009109196
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.016669568
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.0091959825
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LRPAP1 Gene (Entity type)	0.011033252
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP9 Gene (Entity type)	0.0119712455
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Aurora kinase A Protein (Entity type)	IC50
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCL20 Gene (Entity type)	0.013839493
2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H2AX Gene (Entity type)	-0.0093747135