F2R (Gene)

Description: coagulation factor II thrombin receptor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View F2R's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with F2R.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using F2R.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for F2R.

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Gene Sets (1262)

LINCS L1000 Chem Pert Consensus Sigs (680)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (575)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Withaferin-a Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	-0.007849062
Oxiconazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	-0.005994045
dibutyrylcyclic-gmp Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.008370939
SA-432137 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.009173533
4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.007230345
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	-0.0070719
eugenitol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.009826889
Marbofloxacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.0041576256
RAN-14B Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.010094406
alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	0.004250009