HMGCS1 (Gene)

Description: 3-hydroxy-3-methylglutaryl-CoA synthase 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HMGCS1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HMGCS1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HMGCS1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HMGCS1.

Submit

Gene Sets (3294)

LINCS L1000 Chem Pert Consensus Sigs (2065)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1224)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID103905642 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.0049418155
NTNCB Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.042634744
BMS-191011 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.009531118
AM-92016 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.0072668064
terfenadine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.031310834
PP1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.010704122
SID11114078 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.012698168
lupanine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.0032087562
AVA Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.006134614
ST-4029573 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.013165648