N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABCA8 Gene (Entity type)	0.005569193
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEMA3C Gene (Entity type)	0.006361711
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phosphatidylinositol 4-kinase beta Protein (Entity type)	IC50
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.0064699505
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MGLL Gene (Entity type)	0.006792748
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP7 Gene (Entity type)	-0.007988372
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STX1A Gene (Entity type)	0.008263318
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Voxtalisib Compound (Entity type)	0.3488747477531433
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	-0.006563188
N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDH19 Gene (Entity type)	0.005759872

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABCA8
Gene (Entity type)
0.005569193

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEMA3C
Gene (Entity type)
0.006361711

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phosphatidylinositol 4-kinase beta
Protein (Entity type)
IC50

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
-0.0064699505

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MGLL
Gene (Entity type)
0.006792748

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP7
Gene (Entity type)
-0.007988372

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STX1A
Gene (Entity type)
0.008263318

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Voxtalisib
Compound (Entity type)
0.3488747477531433

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
-0.006563188

N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDH19
Gene (Entity type)
0.005759872

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