2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	0.008556543
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FGF13 Gene (Entity type)	0.004626644
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phospholipase A2, membrane associated Protein (Entity type)	IC50
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BMP4 Gene (Entity type)	0.00586507
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	dorzolamide Compound (Entity type)	0.4168215095996856
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNTT Gene (Entity type)	0.004583494
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0044226167
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	0.008184418
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADH1B Gene (Entity type)	-0.0040859547
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BAD Gene (Entity type)	0.0049806833

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
0.008556543

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FGF13
Gene (Entity type)
0.004626644

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phospholipase A2, membrane associated
Protein (Entity type)
IC50

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BMP4
Gene (Entity type)
0.00586507

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
dorzolamide
Compound (Entity type)
0.4168215095996856

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNTT
Gene (Entity type)
0.004583494

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.0044226167

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
0.008184418

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADH1B
Gene (Entity type)
-0.0040859547

2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BAD
Gene (Entity type)
0.0049806833

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