NVL (Gene)

Entrez Gene ID: 4931

Description: nuclear VCP like

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NVL's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NVL.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NVL.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NVL.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NVL.

Gene Sets (3093)

LINCS L1000 Chem Pert Consensus Sigs (1266)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1824)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Chlorpropamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	0.00713234
NTNCB Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.01266044
miglitol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0036661013
ST-012015 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.013920631
medronic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0045870417
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0037564305
N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]-ethoxy]-4-pyrimidinyl]-N'-propylsulfamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	0.0053433566
MDM2-inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.009017624
(S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	0.004939198
foliosidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	0.0067759403

Chlorpropamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
0.00713234

NTNCB
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.01266044

miglitol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.0036661013

ST-012015
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.013920631

medronic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.0045870417

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.0037564305

N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]-ethoxy]-4-pyrimidinyl]-N'-propylsulfamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
0.0053433566

MDM2-inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.009017624

(S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
0.004939198

foliosidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
0.0067759403

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.