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imipramine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View imipramine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	imipramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.011248748
	imipramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNPDA1 Gene (Entity type)	0.00442883
	imipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.004130629
	imipramine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent serotonin transporter Protein (Entity type)	Ki
	imipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINA3 Gene (Entity type)	-0.0042683748
	imipramine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent noradrenaline transporter Protein (Entity type)	Ki
	imipramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPC1 Gene (Entity type)	0.0051457174
	imipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFIT1 Gene (Entity type)	-0.0038539802
	imipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	-0.003911651
	imipramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCR Gene (Entity type)	0.004594063

imipramine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.011248748

imipramine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GNPDA1
Gene (Entity type)
0.00442883

imipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.004130629

imipramine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent serotonin transporter
Protein (Entity type)
Ki

imipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINA3
Gene (Entity type)
-0.0042683748

imipramine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent noradrenaline transporter
Protein (Entity type)
Ki

imipramine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPC1
Gene (Entity type)
0.0051457174

imipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFIT1
Gene (Entity type)
-0.0038539802

imipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI6
Gene (Entity type)
-0.003911651

imipramine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCR
Gene (Entity type)
0.004594063

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