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ledipasvir (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ledipasvir's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	ledipasvir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID3 Gene (Entity type)	-0.0035684782
	ledipasvir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.004185283
	ledipasvir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GSDME Gene (Entity type)	0.0033744269
	ledipasvir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.0038175273
	ledipasvir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI44L Gene (Entity type)	-0.004590713
	ledipasvir Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rilpivirine Compound (Entity type)	0.277445912361145
	ledipasvir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADH1B Gene (Entity type)	0.003760311
	ledipasvir Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one Compound (Entity type)	0.2998139262199402
	Rilpivirine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ledipasvir Compound (Entity type)	0.277445912361145
	ledipasvir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.003420129

ledipasvir
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID3
Gene (Entity type)
-0.0035684782

ledipasvir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.004185283

ledipasvir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GSDME
Gene (Entity type)
0.0033744269

ledipasvir
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.0038175273

ledipasvir
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI44L
Gene (Entity type)
-0.004590713

ledipasvir
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Rilpivirine
Compound (Entity type)
0.277445912361145

ledipasvir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADH1B
Gene (Entity type)
0.003760311

ledipasvir
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Compound (Entity type)
0.2998139262199402

Rilpivirine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ledipasvir
Compound (Entity type)
0.277445912361145

ledipasvir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.003420129

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