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alvimopan (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View alvimopan's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	alvimopan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM255A Gene (Entity type)	0.0040233093
	alvimopan Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Kappa-type opioid receptor Protein (Entity type)	Ki
	alvimopan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	C2CD5 Gene (Entity type)	0.004501915
	alvimopan Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Postoperative ileus Disease or Phenotype (Entity type)
	alvimopan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL2 Gene (Entity type)	0.0042086323
	alvimopan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSAP Gene (Entity type)	-0.004418142
	alvimopan Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PF-03084014 Compound (Entity type)	0.4503678381443023
	alvimopan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WSB1 Gene (Entity type)	0.004203714
	alvimopan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.0051988657
	alvimopan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	-0.0050129215

alvimopan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM255A
Gene (Entity type)
0.0040233093

alvimopan
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Kappa-type opioid receptor
Protein (Entity type)
Ki

alvimopan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
C2CD5
Gene (Entity type)
0.004501915

alvimopan
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Postoperative ileus
Disease or Phenotype (Entity type)

alvimopan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL2
Gene (Entity type)
0.0042086323

alvimopan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSAP
Gene (Entity type)
-0.004418142

alvimopan
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PF-03084014
Compound (Entity type)
0.4503678381443023

alvimopan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
WSB1
Gene (Entity type)
0.004203714

alvimopan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.0051988657

alvimopan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
-0.0050129215

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