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Panobinostat (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Panobinostat's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Panobinostat Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	HC-toxin Compound (Entity type)	0.8746669292449951
	Panobinostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	0.013739368
	Panobinostat Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Polyamine deacetylase HDAC10 Protein (Entity type)	IC50
	Panobinostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	0.01664596
	Panobinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GBE1 Gene (Entity type)	-0.017362248
	Quisinostat Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Panobinostat Compound (Entity type)	0.9138470888137816
	Panobinostat Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide Compound (Entity type)	0.8440876603126526
	Panobinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINH1 Gene (Entity type)	-0.017661272
	Panobinostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAOB Gene (Entity type)	0.013562505
	Panobinostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCMT1 Gene (Entity type)	0.013530613

Panobinostat
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
HC-toxin
Compound (Entity type)
0.8746669292449951

Panobinostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
0.013739368

Panobinostat
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Polyamine deacetylase HDAC10
Protein (Entity type)
IC50

Panobinostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
0.01664596

Panobinostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GBE1
Gene (Entity type)
-0.017362248

Quisinostat
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Panobinostat
Compound (Entity type)
0.9138470888137816

Panobinostat
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide
Compound (Entity type)
0.8440876603126526

Panobinostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINH1
Gene (Entity type)
-0.017661272

Panobinostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAOB
Gene (Entity type)
0.013562505

Panobinostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCMT1
Gene (Entity type)
0.013530613

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