N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	-0.0074530863
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA1A Gene (Entity type)	-0.013632786
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0074896975
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CBS Gene (Entity type)	-0.006999507
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.0069610667
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MYC Gene (Entity type)	0.010312635
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDOC Gene (Entity type)	-0.0071169734
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.008512648
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHGDH Gene (Entity type)	-0.0083100535
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA6 Gene (Entity type)	-0.0062616733

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
-0.0074530863

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA1A
Gene (Entity type)
-0.013632786

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGB2
Gene (Entity type)
0.0074896975

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CBS
Gene (Entity type)
-0.006999507

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.0069610667

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MYC
Gene (Entity type)
0.010312635

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDOC
Gene (Entity type)
-0.0071169734

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.008512648

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHGDH
Gene (Entity type)
-0.0083100535

N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA6
Gene (Entity type)
-0.0062616733

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Knowledge Graph Assertions

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