2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CAVIN2 Gene (Entity type)	-0.0028790834
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMC1A Gene (Entity type)	0.003577658
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HAT1 Gene (Entity type)	0.0036373618
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	eperezolid Compound (Entity type)	0.3074907660484314
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD36 Gene (Entity type)	-0.0030144467
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EFNA1 Gene (Entity type)	-0.0039344765
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A2 Gene (Entity type)	0.0050523733
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.0032910279
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	0.005649401
2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	0.0048272912

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CAVIN2
Gene (Entity type)
-0.0028790834

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMC1A
Gene (Entity type)
0.003577658

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HAT1
Gene (Entity type)
0.0036373618

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
eperezolid
Compound (Entity type)
0.3074907660484314

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD36
Gene (Entity type)
-0.0030144467

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EFNA1
Gene (Entity type)
-0.0039344765

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A2
Gene (Entity type)
0.0050523733

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.0032910279

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MYLK
Gene (Entity type)
0.005649401

2-(Furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]-piperazin-1-yl]ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
0.0048272912

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