[11C]doxepin (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [11C]doxepin's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[<sup>11</sup>C]doxepin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.0026233355
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.0035132363
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LPL Gene (Entity type)	-0.0029602102
[<sup>11</sup>C]doxepin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Pasireotide Compound (Entity type)	0.2627798318862915
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCOLN1 Gene (Entity type)	-0.002988946
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NQO1 Gene (Entity type)	-0.003446299
[<sup>11</sup>C]doxepin Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Sleeplessness Disease or Phenotype (Entity type)
[<sup>11</sup>C]doxepin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDH2 Gene (Entity type)	0.0031410863
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.003797184
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSTA Gene (Entity type)	-0.0031915207

[11C]doxepin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.0026233355

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.0035132363

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LPL
Gene (Entity type)
-0.0029602102

[11C]doxepin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Pasireotide
Compound (Entity type)
0.2627798318862915

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCOLN1
Gene (Entity type)
-0.002988946

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NQO1
Gene (Entity type)
-0.003446299

[11C]doxepin
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Sleeplessness
Disease or Phenotype (Entity type)

[11C]doxepin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDH2
Gene (Entity type)
0.0031410863

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.003797184

[11C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CSTA
Gene (Entity type)
-0.0031915207

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Knowledge Graph Assertions

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CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.

[<sup>11</sup>C]doxepin (Compound)

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Knowledge Graph Assertions

Knowledge Graph Assertions

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Knowledge Graph Assertions