EPCAM (Gene)

Ensembl Gene ID: ENSG00000119888

Entrez Gene ID: 4072

Description: epithelial cell adhesion molecule

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EPCAM's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EPCAM.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EPCAM.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EPCAM.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EPCAM.

Gene Sets (5737)

LINCS L1000 Chem Pert Consensus Sigs (1389)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (34)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1434)

A gene set library provided by LINCS

rummageo gene perturbations (144)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (11)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (348)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2059)

A gene set library provided by LINCS

rummageo chemical perturbations (247)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (8)

A gene set library provided by GTEx

HuBMAP ASCT-B (50)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-iminobiotin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.005106982
HC-toxin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.016644271
fexofenadine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	0.0033964387
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.0050017564
(R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.0040167533
Tyrphostin-47 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.014411417
maltobionic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	0.005580918
[<sup>11</sup>C]doxepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.0035132363
1-monopalmitin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	0.011798975
SA-427636 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.012971584

2-iminobiotin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.005106982

HC-toxin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.016644271

fexofenadine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
0.0033964387

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.0050017564

(R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.0040167533

Tyrphostin-47
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.014411417

maltobionic-acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
0.005580918

[<sup>11</sup>C]doxepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.0035132363

1-monopalmitin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
0.011798975

SA-427636
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.012971584

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.