C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
exemestane Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	0.4597494900226593
teroxirone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	0.2752170264720917
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 5A Protein (Entity type)
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCNA Gene (Entity type)	0.008095922
N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-hydrazine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	0.2694095969200134
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HOXC6 Gene (Entity type)	0.0044243624
Primaquine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	0.4876437187194824
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CILP Gene (Entity type)	0.0058783367
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COMP Gene (Entity type)	0.0045296852
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DPP4 Gene (Entity type)	0.0043641264

exemestane
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
0.4597494900226593

teroxirone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
0.2752170264720917

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 5A
Protein (Entity type)

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCNA
Gene (Entity type)
0.008095922

N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-hydrazine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
0.2694095969200134

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HOXC6
Gene (Entity type)
0.0044243624

Primaquine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
0.4876437187194824

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CILP
Gene (Entity type)
0.0058783367

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COMP
Gene (Entity type)
0.0045296852

C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide (Sumatriptan)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DPP4
Gene (Entity type)
0.0043641264

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