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Defactinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Defactinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Defactinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FBP1 Gene (Entity type)	0.005695915
	Defactinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	-0.0066050203
	Defactinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BEX1 Gene (Entity type)	0.0065306015
	Defactinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STS Gene (Entity type)	0.005170564
	Defactinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALCAM Gene (Entity type)	0.00523546
	Defactinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	0.005886254
	Defactinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF1AY Gene (Entity type)	-0.006395818
	Defactinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNAI1 Gene (Entity type)	-0.0063295527
	Defactinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FADS1 Gene (Entity type)	-0.004372791
	Defactinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.005020256

Defactinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FBP1
Gene (Entity type)
0.005695915

Defactinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A9
Gene (Entity type)
-0.0066050203

Defactinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BEX1
Gene (Entity type)
0.0065306015

Defactinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STS
Gene (Entity type)
0.005170564

Defactinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALCAM
Gene (Entity type)
0.00523546

Defactinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
0.005886254

Defactinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EIF1AY
Gene (Entity type)
-0.006395818

Defactinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNAI1
Gene (Entity type)
-0.0063295527

Defactinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FADS1
Gene (Entity type)
-0.004372791

Defactinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.005020256

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