Afatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Afatinib's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.00612757
Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	-0.0057788813
Afatinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Epidermal growth factor receptor positive non-small cell lung cancer Disease or Phenotype (Entity type)
Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMP3 Gene (Entity type)	-0.0049459944
Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	-0.005105124
Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.008991934
Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CBS Gene (Entity type)	0.006973538
Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASS1 Gene (Entity type)	0.0070086727
WZ4002 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Afatinib Compound (Entity type)	0.425775408744812
Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	-0.009250522

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.