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Afatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Afatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.00612757
	Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	-0.0057788813
	Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMP3 Gene (Entity type)	-0.0049459944
	Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	-0.005105124
	Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.008991934
	Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CBS Gene (Entity type)	0.006973538
	Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASS1 Gene (Entity type)	0.0070086727
	WZ4002 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Afatinib Compound (Entity type)	0.425775408744812
	Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	-0.009250522
	Afatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.00608343

Afatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.00612757

Afatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
-0.0057788813

Afatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMP3
Gene (Entity type)
-0.0049459944

Afatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH1A3
Gene (Entity type)
-0.005105124

Afatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.008991934

Afatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CBS
Gene (Entity type)
0.006973538

Afatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASS1
Gene (Entity type)
0.0070086727

WZ4002
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Afatinib
Compound (Entity type)
0.425775408744812

Afatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TACSTD2
Gene (Entity type)
-0.009250522

Afatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IER3
Gene (Entity type)
-0.00608343

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