5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-1D adrenergic receptor Protein (Entity type)	-
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF589 Gene (Entity type)	-0.008726412
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	-0.00883466
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Iobenguane Compound (Entity type)	0.2836729884147644
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	gitoxigenin Compound (Entity type)	0.2729003131389618
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNAS Gene (Entity type)	0.012191298
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.014992176
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SOX11 Gene (Entity type)	0.01444771
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHI3L1 Gene (Entity type)	0.0085447775
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-1B adrenergic receptor Protein (Entity type)	Ki

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-1D adrenergic receptor
Protein (Entity type)
-

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF589
Gene (Entity type)
-0.008726412

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
-0.00883466

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Iobenguane
Compound (Entity type)
0.2836729884147644

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
gitoxigenin
Compound (Entity type)
0.2729003131389618

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GNAS
Gene (Entity type)
0.012191298

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.014992176

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SOX11
Gene (Entity type)
0.01444771

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHI3L1
Gene (Entity type)
0.0085447775

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-1B adrenergic receptor
Protein (Entity type)
Ki

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Knowledge Graph Assertions

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