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Iobenguane (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Iobenguane's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Iobenguane Compound (Entity type)	0.2836729884147644
	Iobenguane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG3 Gene (Entity type)	-0.0082322145
	Iobenguane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.008412878
	Iobenguane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFITM2 Gene (Entity type)	0.007494919
	Iobenguane Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(6S,9S,12S,13S,17S,20R,21S)-13,21-dihydroxy-12,20-diisobutyl-6,9-diisopropyl-2,17-dimethyl-4,7,10,15,18-pentaoxo-5,8,11,16,19-pentaazatricosan-23-oic acid Compound (Entity type)	0.3199676275253296
	Iobenguane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EMX2 Gene (Entity type)	0.010211411
	Iobenguane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLCO3A1 Gene (Entity type)	-0.008185021
	Iobenguane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NTRK2 Gene (Entity type)	-0.008720926
	Iobenguane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFD Gene (Entity type)	-0.009391259
	Iobenguane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	0.006930928

5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Iobenguane
Compound (Entity type)
0.2836729884147644

Iobenguane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEG3
Gene (Entity type)
-0.0082322145

Iobenguane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.008412878

Iobenguane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFITM2
Gene (Entity type)
0.007494919

Iobenguane
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(6S,9S,12S,13S,17S,20R,21S)-13,21-dihydroxy-12,20-diisobutyl-6,9-diisopropyl-2,17-dimethyl-4,7,10,15,18-pentaoxo-5,8,11,16,19-pentaazatricosan-23-oic acid
Compound (Entity type)
0.3199676275253296

Iobenguane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EMX2
Gene (Entity type)
0.010211411

Iobenguane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLCO3A1
Gene (Entity type)
-0.008185021

Iobenguane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NTRK2
Gene (Entity type)
-0.008720926

Iobenguane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFD
Gene (Entity type)
-0.009391259

Iobenguane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
0.006930928

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