Crizotinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Crizotinib's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Crizotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCR Gene (Entity type)	0.004565198
Crizotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Mer Protein (Entity type)	Kd
Crizotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CADM1 Gene (Entity type)	-0.0033508532
Crizotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage-stimulating protein receptor Protein (Entity type)	Kd
Crizotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID3 Gene (Entity type)	-0.0033793258
Crizotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	0.0036802415
Crizotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FADS2 Gene (Entity type)	0.0045492365
Crizotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Hepatocyte growth factor receptor Protein (Entity type)	IC50
Crizotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.008443191
Crizotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FASN Gene (Entity type)	0.0052709584

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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