Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VAT1 Gene (Entity type)	-0.0049183937
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OLFM4 Gene (Entity type)	0.0077222595
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STEAP1 Gene (Entity type)	0.005542225
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGFBP2 Gene (Entity type)	-0.005859388
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	0.0072820713
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.005539893
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.0055727097
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NAMPT Gene (Entity type)	-0.0053705634
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.0054892427
Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB2 Gene (Entity type)	-0.005123549

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
VAT1
Gene (Entity type)
-0.0049183937

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OLFM4
Gene (Entity type)
0.0077222595

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STEAP1
Gene (Entity type)
0.005542225

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGFBP2
Gene (Entity type)
-0.005859388

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A9
Gene (Entity type)
0.0072820713

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.005539893

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.0055727097

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NAMPT
Gene (Entity type)
-0.0053705634

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP4B1
Gene (Entity type)
0.0054892427

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINB2
Gene (Entity type)
-0.005123549

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Knowledge Graph Assertions

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