2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	0.0028426491
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	orciprenaline Compound (Entity type)	0.4274737536907196
Minoxidil Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	0.3867189884185791
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	0.002086763
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD52 Gene (Entity type)	-0.0023234054
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.002492611
Clinofibrate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	0.2583333551883697
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GADD45A Gene (Entity type)	-0.0030923465
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Temozolomide Compound (Entity type)	0.4003238677978515
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VEGFA Gene (Entity type)	-0.002518376

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
0.0028426491

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
orciprenaline
Compound (Entity type)
0.4274737536907196

Minoxidil
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
0.3867189884185791

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
0.002086763

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD52
Gene (Entity type)
-0.0023234054

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.002492611

Clinofibrate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
0.2583333551883697

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GADD45A
Gene (Entity type)
-0.0030923465

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Temozolomide
Compound (Entity type)
0.4003238677978515

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
VEGFA
Gene (Entity type)
-0.002518376

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Knowledge Graph Assertions

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