MDK (Gene)

Entrez Gene ID: 4192

Description: midkine

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MDK's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MDK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MDK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MDK.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MDK.

Gene Sets (5335)

LINCS L1000 Chem Pert Consensus Sigs (1243)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1194)

A gene set library provided by LINCS

rummageo gene perturbations (236)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (437)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1832)

A gene set library provided by LINCS

rummageo chemical perturbations (372)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Latamoxef Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	-0.023604995
Telatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	0.0036616116
SA-1458487 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	0.011098668
daphnetin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	-0.010962999
Kaempferol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	-0.016302729
bacampicilline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	-0.029349118
KFGENEBIN:MDK-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)
2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	0.002086763
(2,3-dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	0.006939081
SA-243929 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MDK Gene (Entity type)	-0.0154693555

Latamoxef
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
-0.023604995

Telatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
0.0036616116

SA-1458487
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
0.011098668

daphnetin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
-0.010962999

Kaempferol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
-0.016302729

bacampicilline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
-0.029349118

KFGENEBIN:MDK-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)

2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
0.002086763

(2,3-dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
0.006939081

SA-243929
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MDK
Gene (Entity type)
-0.0154693555

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Knowledge Graph Assertions

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CFDE Workbench

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.