1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Stromelysin-2 Protein (Entity type)	IC50
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage metalloelastase Protein (Entity type)	IC50
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Neutrophil collagenase Protein (Entity type)	IC50
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Collagenase 3 Protein (Entity type)	IC50
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Stromelysin-1 Protein (Entity type)	IC50
1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Stromelysin-2
Protein (Entity type)
IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Macrophage metalloelastase
Protein (Entity type)
IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Neutrophil collagenase
Protein (Entity type)
IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Collagenase 3
Protein (Entity type)
IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Stromelysin-1
Protein (Entity type)
IC50

1-[(3-{[3-({[(4-Oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]oxy}propyl)sulfonyl]piperidine-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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