72 kDa type IV collagenase (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 72 kDa type IV collagenase 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N4-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N1-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	Ki
5-(4-phenoxyphenyl)-5-(4-tetradecanoyl-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
5-(4-Phenoxyphenyl)-5-(4-(6-(trifluoromethyl)nicotinoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-octyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	Ki
4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-methylbenzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
2-(Benzyl-pentafluorobenzenesulfonyl-amino)-4-methyl-pentanoic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	Ki
(R)-N1-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-2-[3-(2-fluoro-biphenyl-4-yl)-propyl]-N4-hydroxy-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
1-Ethyl-N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}-sulfonyl)piperidine-4-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
N-hydroxy-2-methyl-2-{4-[2-methyl-3'-(2-methylamino-ethoxy)-biphenyl-4-yl]-piperidine-1-sulfonyl}-propionamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50

N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
Ki

5-(4-phenoxyphenyl)-5-(4-tetradecanoyl-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

5-(4-Phenoxyphenyl)-5-(4-(6-(trifluoromethyl)nicotinoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

(R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-octyl-succinamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
Ki

4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-methylbenzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

2-(Benzyl-pentafluorobenzenesulfonyl-amino)-4-methyl-pentanoic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
Ki

(R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-2-[3-(2-fluoro-biphenyl-4-yl)-propyl]-N*4*-hydroxy-succinamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

1-Ethyl-N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}-sulfonyl)piperidine-4-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

N-hydroxy-2-methyl-2-{4-[2-methyl-3'-(2-methylamino-ethoxy)-biphenyl-4-yl]-piperidine-1-sulfonyl}-propionamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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