2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TCIM Gene (Entity type)	0.010864884
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TNFAIP2 Gene (Entity type)	0.009058996
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC2A3 Gene (Entity type)	-0.010150239
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	naloxone Compound (Entity type)	0.2676902711391449
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Gossypetin Compound (Entity type)	0.3011670708656311
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OXTR Gene (Entity type)	0.012521169
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	-0.0132136475
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	-0.011092215
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOXC6 Gene (Entity type)	-0.010263007
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLIN2 Gene (Entity type)	-0.014430078

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TCIM
Gene (Entity type)
0.010864884

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TNFAIP2
Gene (Entity type)
0.009058996

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC2A3
Gene (Entity type)
-0.010150239

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
naloxone
Compound (Entity type)
0.2676902711391449

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Gossypetin
Compound (Entity type)
0.3011670708656311

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OXTR
Gene (Entity type)
0.012521169

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
-0.0132136475

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
-0.011092215

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOXC6
Gene (Entity type)
-0.010263007

2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLIN2
Gene (Entity type)
-0.014430078

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Knowledge Graph Assertions

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