(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Non-Small Cell Lung Carcinoma Disease or Phenotype (Entity type)
	(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	GTPase KRas Protein (Entity type)	IC50

(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Non-Small Cell Lung Carcinoma
Disease or Phenotype (Entity type)

(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-pyrido[2,3-d]-pyrimidin-2(1H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
GTPase KRas
Protein (Entity type)
IC50

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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