10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DAPK1 Gene (Entity type)	-0.0080644125
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.009275497
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	17-beta-hydroxysteroid dehydrogenase type 3 Protein (Entity type)	IC50
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.010843245
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GATM Gene (Entity type)	0.009235779
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GABRP Gene (Entity type)	0.008127704
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	-0.015248561
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CACNA2D2 Gene (Entity type)	-0.0094731115
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BSG Gene (Entity type)	-0.008099785
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RASGRP1 Gene (Entity type)	-0.0082137

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DAPK1
Gene (Entity type)
-0.0080644125

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RRM2
Gene (Entity type)
0.009275497

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
17-beta-hydroxysteroid dehydrogenase type 3
Protein (Entity type)
IC50

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
-0.010843245

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GATM
Gene (Entity type)
0.009235779

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GABRP
Gene (Entity type)
0.008127704

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
-0.015248561

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CACNA2D2
Gene (Entity type)
-0.0094731115

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BSG
Gene (Entity type)
-0.008099785

10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RASGRP1
Gene (Entity type)
-0.0082137

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