(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RHOBTB3 Gene (Entity type)	-0.0062081004
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RNASE1 Gene (Entity type)	0.003904852
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GAL Gene (Entity type)	0.0038839967
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCR4 Gene (Entity type)	0.0040013213
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	0.0038138619
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.005934621
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SUV39H1 Gene (Entity type)	0.0037421037
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPTX2 Gene (Entity type)	0.003980086
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SORBS3 Gene (Entity type)	0.003936261
(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RASGRP1 Gene (Entity type)	-0.004615451

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RHOBTB3
Gene (Entity type)
-0.0062081004

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RNASE1
Gene (Entity type)
0.003904852

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GAL
Gene (Entity type)
0.0038839967

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCR4
Gene (Entity type)
0.0040013213

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
0.0038138619

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.005934621

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SUV39H1
Gene (Entity type)
0.0037421037

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPTX2
Gene (Entity type)
0.003980086

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SORBS3
Gene (Entity type)
0.003936261

(2S,4S)-4-fluoro-1-(2-(2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-ylamino)acetyl)pyrrolidine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RASGRP1
Gene (Entity type)
-0.004615451

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